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Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation
Translocation of mRNA and tRNA through the ribosome is a crucial step in protein synthesis, whose mechanism is not yet understood. The crystal structures of three Thermus ribosome·tRNA·mRNA·EF-G complexes trapped with GDPNP or fusidic acid reveal conformational changes occurring during intermediate...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979973/ https://ncbi.nlm.nih.gov/pubmed/23812722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1236086 |
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