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Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation

Translocation of mRNA and tRNA through the ribosome is a crucial step in protein synthesis, whose mechanism is not yet understood. The crystal structures of three Thermus ribosome·tRNA·mRNA·EF-G complexes trapped with GDPNP or fusidic acid reveal conformational changes occurring during intermediate...

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Hlavní autoři: Zhou, Jie, Lancaster, Laura, Donohue, John Paul, Noller, Harry F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979973/
https://ncbi.nlm.nih.gov/pubmed/23812722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1236086
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