A dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-β(1–42)-injected mice

Due to the impermeability of the blood–brain barrier and the nonselective distribution of drugs in the brain, the therapeutic access to intractable neurological disorders is challenging. In this study, dual brain-targeting polymersomes (POs) functionalized by transferrin and Tet-1 peptide (Tf/Tet-1-...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Jia, Tingting, Sun, Zhiguo, Lu, Ying, Gao, Jie, Zou, Hao, Xie, Fangyuan, Zhang, Guoqing, Xu, Hao, Sun, Duxin, Yu, Yuan, Zhong, Yanqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981163/
https://ncbi.nlm.nih.gov/pubmed/27540290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S94622
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