Suppression of glymphatic fluid transport in a mouse model of Alzheimer’s disease

Glymphatic transport, defined as cerebrospinal fluid (CSF) peri-arterial inflow into brain, and interstitial fluid (ISF) clearance, is reduced in the aging brain. However, it is unclear whether glymphatic transport affects the distribution of soluble Aβ in Alzheimer’s disease (AD). In wild type mice...

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Veröffentlicht in:Neurobiol Dis
Hauptverfasser: Peng, Weiguo, Achariyar, Thiyagarajan M, Li, Baoman, Liao, Yonghong, Mestre, Humberto, Hitomi, Emi, Regan, Sean, Kasper, Tristan, Peng, Sisi, Ding, Fengfei, Benveniste, Helene, Nedergaard, Maiken, Deane, Rashid
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980916/
https://ncbi.nlm.nih.gov/pubmed/27234656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.05.015
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