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Early activation of MyD88-mediated autophagy sustains HSV-1 replication in human monocytic THP-1 cells

Autophagy is a cellular degradation pathway that exerts numerous functions in vital biological processes. Among these, it contributes to both innate and adaptive immunity. On the other hand, pathogens have evolved strategies to manipulate autophagy for their own advantage. By monitoring autophagic m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Siracusano, Gabriel, Venuti, Assunta, Lombardo, Daniele, Mastino, Antonio, Esclatine, Audrey, Sciortino, Maria Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980660/
https://ncbi.nlm.nih.gov/pubmed/27509841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31302
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