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Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA
The development of a ligand that is capable of distinguishing among the wide variety of G-quadruplex structures and targeting telomeres to treat cancer is particularly challenging. In this study, the ability of two anthraquinone telomerase inhibitors (NSC749235 and NSC764638) to target telomeric G-q...
Kaydedildi:
| Yayımlandı: | Sci Rep |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980623/ https://ncbi.nlm.nih.gov/pubmed/27511133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31019 |
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