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Molecular Recognition of the Hybrid-Type G-Quadruplexes in Human Telomeres

G-quadruplex (G4) DNA secondary structures formed in human telomeres have been shown to inhibit cancer-specific telomerase and alternative lengthening of telomere (ALT) pathways. Thus, human telomeric G-quadruplexes are considered attractive targets for anticancer drugs. Human telomeric G-quadruplex...

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Publicado en:Molecules
Main Authors: Wu, Guanhui, Chen, Luying, Liu, Wenting, Yang, Danzhou
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514847/
https://ncbi.nlm.nih.gov/pubmed/31013622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24081578
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