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Immune Checkpoint Blockade in Cancer Therapy
Immunologic checkpoint blockade with antibodies that target cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) and the programmed cell death protein 1 pathway (PD-1/PD-L1) have demonstrated promise in a variety of malignancies. Ipilimumab (CTLA-4) and pembrolizumab (PD-1) are approved by the US Fo...
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| Veröffentlicht in: | J Clin Oncol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Clinical Oncology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980573/ https://ncbi.nlm.nih.gov/pubmed/25605845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.59.4358 |
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