Llwytho...

p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease

Cyclin-dependent kinase 5 (CDK5) plays important roles in synaptic function. Its unregulated over-activation has been, however, associated with neurodegeneration in Alzheimer’s disease. Our previous studies revealed that CDK5 silencing ameliorates tauopathy and spatial memory impairment in the 3xTgA...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurochem
Prif Awduron: Uribe-Arias, Alejandro, Posada-Duque, Rafael Andrés, González-Billault, Christian, Villegas, Andrés, Lopera, Francisco, Cardona-Gómez, Gloria Patricia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980216/
https://ncbi.nlm.nih.gov/pubmed/27273428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13697
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