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p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease
Cyclin-dependent kinase 5 (CDK5) plays important roles in synaptic function. Its unregulated over-activation has been, however, associated with neurodegeneration in Alzheimer’s disease. Our previous studies revealed that CDK5 silencing ameliorates tauopathy and spatial memory impairment in the 3xTgA...
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| Veröffentlicht in: | J Neurochem |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980216/ https://ncbi.nlm.nih.gov/pubmed/27273428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13697 |
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