Effects of nicotine in combination with drugs described as positive allosteric nicotinic acetylcholine receptor modulators in vitro: discriminative stimulus and hypothermic effects in mice

Some drugs that are positive allosteric nAChR modulators in vitro, desformylflustrabromine (dFBr), PNU-120596 and LY 2087101, have not been fully characterized in vivo. These drugs were examined for their capacity to share or modify the hypothermic and discriminative stimulus effects of nicotine (1...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Moerke, Megan J., de Moura, Fernando B., Koek, Wouter, McMahon, Lance R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980200/
https://ncbi.nlm.nih.gov/pubmed/27238974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.05.032
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