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JWH-018 in rhesus monkeys: differential antagonism of discriminative stimulus, rate-decreasing, and hypothermic effects
Several effects of the abused synthetic cannabinoid JWH-018 were compared to those of Δ(9)-tetrahydrocannabinol (Δ(9)-THC) in rhesus monkeys. JWH-018 (0.1 mg/kg i.v.) was established as a discriminative stimulus and rimonabant was used to examine mechanisms responsible for discrimination as well as...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146721/ https://ncbi.nlm.nih.gov/pubmed/24972243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.06.023 |
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