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Geometry matters: inverse cytotoxic relationship for cis/trans-Ru(II) polypyridyl complexes from cis/trans-[PtCl(2)(NH(3))(2)]

Two thermally activated ruthenium(II) polypyridyl complexes, cis-Ru(bpy)(2)Cl(2) and trans-Ru(qpy)Cl(2) were investigated to determine the impact of the geometric arrangement of the exchangable ligands on the potential of the compounds to act as chemotherapeutics. In contrast to the geometry require...

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Dettagli Bibliografici
Pubblicato in:Chem Commun (Camb)
Autori principali: Wachter, Erin, Zamora, Ana, Heidary, David K., Ruiz, José, Glazer, Edith C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980196/
https://ncbi.nlm.nih.gov/pubmed/27352966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc04813g
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