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Similar binding of the carcinostatic drugs cis-[Pt(NH3)2Cl2] and [Ru(NH3)5Cl] Cl2 to tRNAphe and a comparison with the binding of the inactive trans-[Pt(NH3)2Cl2] complex - reluctance in binding to Watson-Crick base pairs within double helix.

A comparative study of the binding of square planar cis- and trans-[Pt(NH3)2Cl2] complexes and the octahedral [Ru(NH3)5(H2O)]3+ complex to tRNAphe from yeast was carried out by X-ray crystallography. Both of the carcinostatic compounds, cis-[Pt(NH3)2Cl2] and [Ru(NH3)5(H2O)]3+ show similarities in th...

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Bibliografiska uppgifter
Huvudupphovsmän: Rubin, J R, Sabat, M, Sundaralingam, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1983
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC326395/
https://ncbi.nlm.nih.gov/pubmed/6353373
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