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The extracellular chaperone clusterin sequesters oligomeric forms of the Aβ(1–40) peptide
In recent genome-wide association studies, the extracellular chaperone protein, clusterin, has been identified as a novel risk factor in Alzheimer’s disease (AD). We have examined the interactions between clusterin and the AD-associated amyloid-β(1–40) peptide (Aβ(1–40)) which is prone to aggregate...
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| Wydane w: | Nat Struct Mol Biol |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979993/ https://ncbi.nlm.nih.gov/pubmed/22179788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2191 |
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