MUC4 is negatively regulated through the Wnt/β-catenin pathway via the Notch effector Hath1 in colorectal cancer

MUC4 is a transmembrane mucin lining the normal colonic epithelium. The aberrant/de novo over-expression of MUC4 is well documented in malignancies of the pancreas, ovary and breast. However, studies have reported the loss of MUC4 expression in the majority of colorectal cancers (CRCs). A MUC4 promo...

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Vydáno v:Genes Cancer
Hlavní autoři: Pai, Priya, Rachagani, Satyanarayana, Dhawan, Punita, Sheinin, Yuri M., Macha, Muzafar A., Qazi, Asif Khurshid, Chugh, Seema, Ponnusamy, Moorthy P., Mallya, Kavita, Pothuraju, Ramesh, Batra, Surinder K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979589/
https://ncbi.nlm.nih.gov/pubmed/27551331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.108
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