Axed MUC4 (MUC4/X) aggravates pancreatic malignant phenotype by activating integrin-β1/FAK/ERK pathway

Alternative splicing is evolving as an eminent player of oncogenic signaling for tumor development and progression. Mucin 4 (MUC4), a type I membrane-bound mucin, is differentially expressed in pancreatic cancer (PC) and plays a critical role in its progression and metastasis. However, the molecular...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biochim Biophys Acta
Auteurs principaux: Jahan, Rahat, Macha, Muzafar A., Rachagani, Satyanarayana, Das, Srustidhar, Smith, Lynette M., Kaur, Sukhwinder, Batra, Surinder K.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047753/
https://ncbi.nlm.nih.gov/pubmed/29777904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.05.008
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