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Curcumin induces crosstalk between autophagy and apoptosis mediated by calcium release from the endoplasmic reticulum, lysosomal destabilization and mitochondrial events

Curcumin, a major active component of turmeric (Curcuma longa, L.), has anticancer effects. In vitro studies suggest that curcumin inhibits cancer cell growth by activating apoptosis, but the mechanism underlying these effects is still unclear. Here, we investigated the mechanisms leading to apoptos...

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Dettagli Bibliografici
Pubblicato in:Cell Death Discov
Autori principali: Moustapha, A, Pérétout, PA, Rainey, NE, Sureau, F, Geze, M, Petit, J-M, Dewailly, E, Slomianny, C, Petit, PX
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979459/
https://ncbi.nlm.nih.gov/pubmed/27551451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.17
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