Curcumin induces crosstalk between autophagy and apoptosis mediated by calcium release from the endoplasmic reticulum, lysosomal destabilization and mitochondrial events

Curcumin, a major active component of turmeric (Curcuma longa, L.), has anticancer effects. In vitro studies suggest that curcumin inhibits cancer cell growth by activating apoptosis, but the mechanism underlying these effects is still unclear. Here, we investigated the mechanisms leading to apoptos...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Moustapha, A, Pérétout, PA, Rainey, NE, Sureau, F, Geze, M, Petit, J-M, Dewailly, E, Slomianny, C, Petit, PX
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979459/
https://ncbi.nlm.nih.gov/pubmed/27551451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.17
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