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Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation

Iron overload, notably caused by hereditary hemochromatosis, is an excess storage of iron in various organs that causes tissue damage and may promote tumorigenesis. To manage that disorder, free iron depletion can be induced by iron chelators like deferoxamine that are of increasing interest also in...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Rainey, Nathan E., Moustapha, Aoula, Saric, Ana, Nicolas, Gael, Sureau, Franck, Petit, Patrice X.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901436/
https://ncbi.nlm.nih.gov/pubmed/31839992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0234-y
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