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Iron chelation by curcumin suppresses both curcumin-induced autophagy and cell death together with iron overload neoplastic transformation

Iron overload, notably caused by hereditary hemochromatosis, is an excess storage of iron in various organs that causes tissue damage and may promote tumorigenesis. To manage that disorder, free iron depletion can be induced by iron chelators like deferoxamine that are of increasing interest also in...

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Dades bibliogràfiques
Publicat a:Cell Death Discov
Autors principals: Rainey, Nathan E., Moustapha, Aoula, Saric, Ana, Nicolas, Gael, Sureau, Franck, Petit, Patrice X.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901436/
https://ncbi.nlm.nih.gov/pubmed/31839992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0234-y
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