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Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2
MAPK-activated protein kinase 2 (MK2) is a checkpoint kinase involved in the DNA damage response. MK2 inhibition enhances the efficacy of chemotherapeutic agents; however, whether MK2 inhibition alone, without concurrent chemotherapy, would attenuate survival of cancer cells has not been investigate...
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| Publicado no: | Cell Death Discov |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979411/ https://ncbi.nlm.nih.gov/pubmed/27551460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.28 |
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