Adenovirus-human immunodeficiency virus (HIV) envelope recombinant vaccines elicit high-titered HIV-neutralizing antibodies in the dog model.

Recombinant human adenoviruses (Ads) (types 4, 5, and 7) expressing the HIV-1 envelope membrane glycoprotein (gp160) were tested for immunogenicity in the dog. Administration of recombinant Ad7-env by intratracheal inoculation resulted in a low serum antibody response to gp160, which developed over...

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Detalhes bibliográficos
Main Authors: Natuk, R J, Chanda, P K, Lubeck, M D, Davis, A R, Wilhelm, J, Hjorth, R, Wade, M S, Bhat, B M, Mizutani, S, Lee, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49794/
https://ncbi.nlm.nih.gov/pubmed/1502197
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