Shedding of Syndecan-1/CXCL1 Complexes by Matrix Metalloproteinase 7 Functions as an Epithelial Checkpoint of Neutrophil Activation

Although neutrophils play critical roles in innate immunity, in excess these cells cause severe tissue damage. Thus, neutrophil activation must be tightly regulated to prevent indiscriminant damage. Previously, we reported that mice lacking matrix metalloproteinase (MMP) 7 are protected from lung in...

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Bibliografische gegevens
Gepubliceerd in:Am J Respir Cell Mol Biol
Hoofdauteurs: Gill, Sean E., Nadler, Samuel T., Li, Qinglang, Frevert, Charles W., Park, Pyong Woo, Chen, Peter, Parks, William C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2016
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979362/
https://ncbi.nlm.nih.gov/pubmed/26934670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0193OC
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