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Syndecan-1 Ectodomain Shedding Is Regulated by the Small GTPase Rab5
The ectodomain shedding of syndecan-1, a major cell surface heparan sulfate proteoglycan, modulates molecular and cellular processes central to the pathogenesis of inflammatory diseases. Syndecan-1 shedding is a highly regulated process in which outside-in signaling accelerates the proteolytic cleav...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2602919/ https://ncbi.nlm.nih.gov/pubmed/18957427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804172200 |
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