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Syndecan-1 Ectodomain Shedding Is Regulated by the Small GTPase Rab5

The ectodomain shedding of syndecan-1, a major cell surface heparan sulfate proteoglycan, modulates molecular and cellular processes central to the pathogenesis of inflammatory diseases. Syndecan-1 shedding is a highly regulated process in which outside-in signaling accelerates the proteolytic cleav...

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Detalhes bibliográficos
Principais autores: Hayashida, Kazutaka, Stahl, Philip D., Park, Pyong Woo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602919/
https://ncbi.nlm.nih.gov/pubmed/18957427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804172200
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