Shedding of Syndecan-1/CXCL1 Complexes by Matrix Metalloproteinase 7 Functions as an Epithelial Checkpoint of Neutrophil Activation

Although neutrophils play critical roles in innate immunity, in excess these cells cause severe tissue damage. Thus, neutrophil activation must be tightly regulated to prevent indiscriminant damage. Previously, we reported that mice lacking matrix metalloproteinase (MMP) 7 are protected from lung in...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Gill, Sean E., Nadler, Samuel T., Li, Qinglang, Frevert, Charles W., Park, Pyong Woo, Chen, Peter, Parks, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979362/
https://ncbi.nlm.nih.gov/pubmed/26934670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0193OC
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