טוען...
CpG site methylation in CRYAA promoter affect transcription factor Sp1 binding in human lens epithelial cells
BACKGROUND: Age-related cataract (ARC) is the leading cause of visual impairment worldwide, and α-crystallin (CRYAA) is the predominant structural protein involved in the maintenance of lens clarity and refractive properties. We previously demonstrated that CRYAA genes undergo epigenetic repression...
שמור ב:
הוצא לאור ב: | BMC Ophthalmol |
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Main Authors: | , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
BioMed Central
2016
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979130/ https://ncbi.nlm.nih.gov/pubmed/27507241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-016-0309-y |
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