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Phase I study of the safety and pharmacokinetics of trabectedin with docetaxel in patients with advanced malignancies
PURPOSE: Combination therapy with trabectedin and docetaxel was evaluated in patients with advanced malignancies. METHODS: In this open-label phase 1 study, docetaxel (60 or 75 mg/m(2); 1-h intravenous infusion) was given on day 1 of a 21-day cycle in combination with escalating doses of trabectedin...
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| Publicado en: | Cancer Chemother Pharmacol |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978949/ https://ncbi.nlm.nih.gov/pubmed/25791363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2705-z |
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