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eEF2 and Ras-GAP SH3 domain-binding protein (G3BP1) modulate stress granule assembly during HIV-1 infection
Stress granules (SG) are translationally silent sites of RNA triage induced by environmental stresses including viral infection. Here we show that HIV-1 Gag blocks SG assembly irrespective of eIF2α-phosphorylation and even when SG assembly is forced by overexpression of Ras-GAP SH3 domain-binding pr...
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| Опубликовано в: : | Nat Commun |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978539/ https://ncbi.nlm.nih.gov/pubmed/25229650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5819 |
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