RasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization

Mitogen activation of mRNA decay pathways likely involves specific endoribonucleases, such as G3BP, a phosphorylation-dependent endoribonuclease that associates with RasGAP in dividing but not quiescent cells. G3BP exclusively cleaves between cytosine and adenine (CA) after a specific interaction wi...

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Bibliographic Details
Main Authors: Tourrière, Hélène, Gallouzi, Imed-eddine, Chebli, Karim, Capony, Jean Paul, Mouaikel, John, van der Geer, Peter, Tazi, Jamal
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC99945/
https://ncbi.nlm.nih.gov/pubmed/11604510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.22.7747-7760.2001
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