Revisiting G3BP1 as a RasGAP Binding Protein: Sensitization of Tumor Cells to Chemotherapy by the RasGAP 317–326 Sequence Does Not Involve G3BP1

RasGAP is a multifunctional protein that controls Ras activity and that is found in chromosomal passenger complexes. It also negatively or positively regulates apoptosis depending on the extent of its cleavage by caspase-3. RasGAP has been reported to bind to G3BP1 (RasGAP SH3-domain-binding protein...

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Bibliografiske detaljer
Main Authors: Annibaldi, Alessandro, Dousse, Aline, Martin, Sophie, Tazi, Jamal, Widmann, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242762/
https://ncbi.nlm.nih.gov/pubmed/22205990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029024
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