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A WXW Motif Is Required for the Anticancer Activity of the TAT-RasGAP(317–326) Peptide
TAT-RasGAP(317–326), a cell-permeable 10-amino acid-long peptide derived from the N2 fragment of p120 Ras GTPase-activating protein (RasGAP), sensitizes tumor cells to apoptosis induced by various anticancer therapies. This RasGAP-derived peptide, by targeting the deleted in liver cancer-1 (DLC1) tu...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156047/ https://ncbi.nlm.nih.gov/pubmed/25008324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576272 |
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