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The senescence-associated secretory phenotype as a driver of tumor growth: does G3BP1 hold the key?

Cellular senescence is a double-edged sword that, depending on the context, acts as either a potent tumor protective mechanism or an age-related driver of diseases such as cancer. Our recent findings show that the rasGAP SH3-binding protein 1 (G3BP1) activates the senescent-associated secretory phen...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Omer, Amr, Di Marco, Sergio, Gallouzi, Imed-Eddine
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849692/
https://ncbi.nlm.nih.gov/pubmed/33553605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1850161
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