Overexpression of X-Linked Inhibitor of Apoptotic Protein (XIAP) Reduces Age-related Neuronal Degeneration in the Mouse Cochlea

Previously, we showed that age-related hearing loss (AHL) was delayed in C57BL6 mice overexpressing X-Linked Inhibitor of Apoptotic Protein (XIAP), and the delayed AHL was associated with attenuated hair cell (HC) loss in XIAP-overexpressing mice. Similar to other reports, the HC loss in aged mice w...

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Vydáno v:Gene Ther
Hlavní autoři: Ruan, Qingwei, Zeng, Shan, Liu, Aiguo, Chen, Zhengnong, Yu, Zhuowei, Zhang, Ruxin, He, jingchun, Bance, Manohar, Robertson, George, Yin, Shankai, Wang, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978537/
https://ncbi.nlm.nih.gov/pubmed/25142138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.77
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