In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period

Aminoglycoside-induced cochlear ototoxicity causes hair cell (HC) loss and results in hearing impairment in patients. Previous studies have developed the concept of an ototoxicity-sensitive period during which the cochleae of young mice are more vulnerable to auditory trauma than adults. Here, we co...

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Detalhes bibliográficos
Main Authors: Sun, Shan, Sun, Mingzhi, Zhang, Yanping, Cheng, Cheng, Waqas, Muhammad, Yu, Huiqian, He, Yingzi, Xu, Bo, Wang, Lei, Wang, Jian, Yin, Shankai, Chai, Renjie, Li, Huawei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166379/
https://ncbi.nlm.nih.gov/pubmed/25278835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00248
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