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CCL21/CCR7 Axis Contributed to CD133(+) Pancreatic Cancer Stem-Like Cell Metastasis via EMT and Erk/NF-κB Pathway

BACKGROUND: Tumor metastasis is driven by malignant cells and stromal cell components of the tumor microenvironment. Cancer stem cells (CSCs) are thought to be responsible for metastasis by altering the tumor microenvironment. Epithelial-mesenchymal transition (EMT) processes contribute to specific...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Zhang, Lirong, Wang, Dongqing, Li, Yumei, Liu, Yanfang, Xie, Xiaodong, Wu, Yingying, Zhou, Yuepeng, Ren, Jing, Zhang, Jianxin, Zhu, Haitao, Su, Zhaoliang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978474/
https://ncbi.nlm.nih.gov/pubmed/27505247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158529
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