CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway

Distant metastasis remains the major failure of nasopharyngeal carcinoma (NPC). In this study, the roles of chemokine C-C motif ligand 2 (CCL2), and its receptor chemokine C-C motif receptor type 2 (CCR2) on NPC metastasis were investigated. Serum CCL2 and CCL2/CCR2 expression level were remarkably...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yang, Jing, Lv, Xing, Chen, Jinna, Xie, Changqing, Xia, Weixiong, Jiang, Chen, Zeng, Tingting, Ye, Yanfang, Ke, Liangru, Yu, Yahui, Liang, Hu, Guan, Xin-Yuan, Guo, Xiang, Xiang, Yanqun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941266/
https://ncbi.nlm.nih.gov/pubmed/26701209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6695
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