Role of the Hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133(+) pancreatic cancer stem-like cells

The initiation and progression of various solid tumors, including pancreatic carcinoma, are driven by a population of cells with stem cell properties, namely cancer stem cells (CSCs). Like their normal counterparts, CSCs are also believed to rely on their own microenvironment termed niches to sustai...

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Autors principals: Zhu, Haitao, Wang, Dongqing, Liu, Yanfang, Su, Zhaoliang, Zhang, Lirong, Chen, Fangfang, Zhou, Yuepeng, Wu, Yingying, Yu, Ming, Zhang, Zhijian, Shao, Genbao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177138/
https://ncbi.nlm.nih.gov/pubmed/24305593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-119
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