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Commensal Bacteria-Induced Inflammasome Activation in Mouse and Human Macrophages Is Dependent on Potassium Efflux but Does Not Require Phagocytosis or Bacterial Viability

Gut commensal bacteria contribute to the pathogenesis of inflammatory bowel disease, in part by activating the inflammasome and inducing secretion of interleukin-1ß (IL-1ß). Although much has been learned about inflammasome activation by bacterial pathogens, little is known about how commensals carr...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Chen, Kejie, Shanmugam, Nanda Kumar N., Pazos, Michael A., Hurley, Bryan P., Cherayil, Bobby J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978417/
https://ncbi.nlm.nih.gov/pubmed/27505062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160937
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