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Protective responses to sublytic complement in the retinal pigment epithelium

The retinal pigment epithelium (RPE) is a key site of injury in inherited and age-related macular degenerations. Abnormal activation of the complement system is a feature of these blinding diseases, yet how the RPE combats complement attack is poorly understood. The complement cascade terminates in...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Tan, Li Xuan, Toops, Kimberly A., Lakkaraju, Aparna
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978296/
https://ncbi.nlm.nih.gov/pubmed/27432952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523061113
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