Bunyamwera orthobunyavirus glycoprotein precursor is processed by cellular signal peptidase and signal peptide peptidase

The M genome segment of Bunyamwera virus (BUNV)—the prototype of both the Bunyaviridae family and the Orthobunyavirus genus—encodes the glycoprotein precursor (GPC) that is proteolytically cleaved to yield two viral structural glycoproteins, Gn and Gc, and a nonstructural protein, NSm. The cleavage...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Shi, Xiaohong, Botting, Catherine H., Li, Ping, Niglas, Mark, Brennan, Benjamin, Shirran, Sally L., Szemiel, Agnieszka M., Elliott, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978261/
https://ncbi.nlm.nih.gov/pubmed/27439867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603364113
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