Bunyamwera orthobunyavirus glycoprotein precursor is processed by cellular signal peptidase and signal peptide peptidase

The M genome segment of Bunyamwera virus (BUNV)—the prototype of both the Bunyaviridae family and the Orthobunyavirus genus—encodes the glycoprotein precursor (GPC) that is proteolytically cleaved to yield two viral structural glycoproteins, Gn and Gc, and a nonstructural protein, NSm. The cleavage...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Shi, Xiaohong, Botting, Catherine H., Li, Ping, Niglas, Mark, Brennan, Benjamin, Shirran, Sally L., Szemiel, Agnieszka M., Elliott, Richard M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978261/
https://ncbi.nlm.nih.gov/pubmed/27439867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603364113
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