Bunyamwera orthobunyavirus glycoprotein precursor is processed by cellular signal peptidase and signal peptide peptidase

The M genome segment of Bunyamwera virus (BUNV)—the prototype of both the Bunyaviridae family and the Orthobunyavirus genus—encodes the glycoprotein precursor (GPC) that is proteolytically cleaved to yield two viral structural glycoproteins, Gn and Gc, and a nonstructural protein, NSm. The cleavage...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shi, Xiaohong, Botting, Catherine H., Li, Ping, Niglas, Mark, Brennan, Benjamin, Shirran, Sally L., Szemiel, Agnieszka M., Elliott, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978261/
https://ncbi.nlm.nih.gov/pubmed/27439867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603364113
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