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Generalized Ensemble Sampling of Enzyme Reaction Free Energy Pathways

Free energy path sampling plays an essential role in computational understanding of chemical reactions, particularly those occurring in enzymatic environments. Among a variety of molecular dynamics simulation approaches, the generalized ensemble sampling strategy is uniquely attractive for the fact...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Wu, Dongsheng, Fajer, Mikolai I., Cao, Liaoran, Cheng, Xiaolin, Yang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978182/
https://ncbi.nlm.nih.gov/pubmed/27498634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.05.012
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