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Hidden Conformation Events in DNA Base Extrusions: A Generalized Ensemble Path Optimization and Equilibrium Simulation Study

DNA base extrusion is a crucial component of many biomolecular processes. Elucidating how bases are selectively extruded from the interiors of double-strand DNAs is pivotal to accurately understanding and efficiently sampling this general type of conformational transitions. In this work, the on-the-...

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Detalhes bibliográficos
Main Authors: Cao, Liaoran, Lv, Chao, Yang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829643/
https://ncbi.nlm.nih.gov/pubmed/24250279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct400198q
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