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Practical and Broadly Applicable Catalytic Enantioselective Additions of Allyl–B(pin) Compounds to Ketones and α-Ketoesters

Broadly applicable methods for efficient and catalytic additions of easy-to-handle allyl–B(pin) (pin = pinacolato) compounds to ketones and acyclic α-ketoesters have been developed. Accordingly, a large array of tertiary alcohols can be obtained in up to >98% yield and 99:1 enantiomeric ratio. At...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Principais autores: Robbins, Daniel W., Lee, KyungA, Silverio, Daniel L., Volkov, Alexey, Torker, Sebastian, Hoveyda, Amir H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978177/
https://ncbi.nlm.nih.gov/pubmed/27273249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603894
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