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DNA Damage Response and Immune Defense: Links and Mechanisms

DNA damage plays a causal role in numerous human pathologies including cancer, premature aging, and chronic inflammatory conditions. In response to genotoxic insults, the DNA damage response (DDR) orchestrates DNA damage checkpoint activation and facilitates the removal of DNA lesions. The DDR can a...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Nakad, Rania, Schumacher, Björn
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977279/
https://ncbi.nlm.nih.gov/pubmed/27555866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00147
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