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Secreted Phosphoprotein 1 and Sex-Specific Differences in Silica-Induced Pulmonary Fibrosis in Mice

BACKGROUND: Fibrotic lung diseases occur predominantly in males, and reports describe better survival in affected females. Male mice are more sensitive to silica-induced lung fibrosis than silica-treated female mice. Secreted phosphoprotein 1 (SPP1, also known as osteopontin) increases in pulmonary...

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Bibliografski detalji
Izdano u:Environ Health Perspect
Glavni autori: Latoche, Joseph D., Ufelle, Alexander Chukwuma, Fazzi, Fabrizio, Ganguly, Koustav, Leikauf, George D., Fattman, Cheryl L.
Format: Artigo
Jezik:Inglês
Izdano: National Institute of Environmental Health Sciences 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977050/
https://ncbi.nlm.nih.gov/pubmed/26955063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1510335
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