TNFR1/Phox Interaction and TNFR1 Mitochondrial Translocation Thwart Silica-Induced Pulmonary Fibrosis

Macrophages play a fundamental role in innate immunity and the pathogenesis of silicosis. Phagocytosis of silica particles is associated with the generation of reactive oxygen species (ROS), secretion of cytokines, such as TNF, and cell death that contribute to silica-induced lung disease. In macrop...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Fazzi, Fabrizio, Njah, Joel, Di Giuseppe, Michelangelo, Winnica, Daniel E., Go, Kristina, Sala, Ernest, St Croix, Claudette M., Watkins, Simon C., Tyurin, Vladimir A., Phinney, Donald G., Fattman, Cheryl L., Leikauf, George D., Kagan, Valerian E., Ortiz, Luis A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: AAI 2014
Θέματα:
Innate Immunity and Inflammation
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977215/
https://ncbi.nlm.nih.gov/pubmed/24623132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103516
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