TNFR1/Phox Interaction and TNFR1 Mitochondrial Translocation Thwart Silica-Induced Pulmonary Fibrosis

Macrophages play a fundamental role in innate immunity and the pathogenesis of silicosis. Phagocytosis of silica particles is associated with the generation of reactive oxygen species (ROS), secretion of cytokines, such as TNF, and cell death that contribute to silica-induced lung disease. In macrop...

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Bibliografski detalji
Glavni autori: Fazzi, Fabrizio, Njah, Joel, Di Giuseppe, Michelangelo, Winnica, Daniel E., Go, Kristina, Sala, Ernest, St Croix, Claudette M., Watkins, Simon C., Tyurin, Vladimir A., Phinney, Donald G., Fattman, Cheryl L., Leikauf, George D., Kagan, Valerian E., Ortiz, Luis A.
Format: Artigo
Jezik:Inglês
Izdano: AAI 2014
Teme:
Innate Immunity and Inflammation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977215/
https://ncbi.nlm.nih.gov/pubmed/24623132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103516
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