Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

Mesenchymal stem cells (MSCs) and macrophages are fundamental components of the stem cell niche and function coordinately to regulate haematopoietic stem cell self-renewal and mobilization. Recent studies indicate that mitophagy and healthy mitochondrial function are critical to the survival of stem...

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Publicado en:Nat Commun
Main Authors: Phinney, Donald G., Di Giuseppe, Michelangelo, Njah, Joel, Sala, Ernest, Shiva, Sruti, St Croix, Claudette M., Stolz, Donna B., Watkins, Simon C., Di, Y. Peter, Leikauf, George D., Kolls, Jay, Riches, David W. H., Deiuliis, Giuseppe, Kaminski, Naftali, Boregowda, Siddaraju V., McKenna, David H., Ortiz, Luis A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Pub. Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598952/
https://ncbi.nlm.nih.gov/pubmed/26442449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9472
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