Innate Immune Activation by Inhaled Lipopolysaccharide, Independent of Oxidative Stress, Exacerbates Silica-Induced Pulmonary Fibrosis in Mice

Acute exacerbations of pulmonary fibrosis are characterized by rapid decrements in lung function. Environmental factors that may contribute to acute exacerbations remain poorly understood. We have previously demonstrated that exposure to inhaled lipopolysaccharide (LPS) induces expression of genes a...

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Autors principals: Brass, David M., Spencer, Jennifer C., Li, Zhuowei, Potts-Kant, Erin, Reilly, Sarah M., Dunkel, Mary K., Latoche, Joseph D., Auten, Richard L., Hollingsworth, John W., Fattman, Cheryl L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397936/
https://ncbi.nlm.nih.gov/pubmed/22815821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040789
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